Meridia    $5.20 |
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| Presentation:- | |||
Meridia (sibutramine hydrochloride monohydrate) Capsules contain 5 mg, 10 mg, or 15 mg of sibutramine hydrochloride monohydrate and are supplied as follows:- 5 mg, blue/yellow capsules imprinted with "Meridia" on the cap and "-5-" on the body, in bottles of 100 capsules. - 10 mg, blue/white capsules imprinted with "Meridia" on the cap and "-10-" on the body, in bottles of 100 capsules. - 15 mg, yellow/white capsules imprinted with "Meridia" on the cap and "-15-" on the body, in bottles of 100 capsules. |
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| Properties:- | |||
| Sibutramine (Meridia) works by suppressing your appetite. This means it makes you feel less hungry. It acts on two chemicals in the brain (neurotransmitters), serotonin and norepinephrine, that affect mood and appetite. Meridia (sibutramine hydrochloride monohydrate) is an orally administered agent for the treatment of obesity. Chemically the active ingredient is a racemic mixture of the and enantiomers of cyclobutanemethanamine 1-(4- chlorophenyl)-N , N - dimethyl - alfa - (2-methylpropyl)-, hydrochloride, monohydrate, and has an empirical formula of C17H 29Cl 2NO. Its molecular weight is 334.33. Sibutramine hydrochloride monohydrate is a white to cream crystalline powder with a solubility of 2.9 mg/ ml in pH 5.2 water. Its octanol water partition coefficient is 30.9 at pH 5.0 Each Meridia capsule contains 5 mg, 10 mg and 15 mg of sibutramine hydrochloride monohydrate. It also contains as inactive ingredients: lactose monohydrate NF; microcrystalline cellulose NF; colloidal silicon dioxide NF; and magnesium stearate NF in a hard gelatin capsule, which contains titanium dioxide USP; gelatin FD&C Blue No.2 (5 and 10 mg capsules only); D&C Yellow No.10 (5 and 15 mg capsules only) and other inactive ingredients. http://www.rxlist.com/cgi/generic/sibutramine.htm |
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| Why It Is Used:- | |||
| Drugs of this class are thought to suppress appetite by inhibiting the reuptake of serotonin, dopamine and norepiniphrine thereby modifying appetite centers in the brain. Sibutramine is prescribed to help people who are obese (those with body mass indexes [BMIs] of 30 or higher) lose weight. In some circumstances, it may be prescribed for people with BMIs of 27 to 30 when they have other conditions (such as diabetes or sleep apnea) that are made worse by being overweight. Sibutramine is intended to be used along with a weight loss diet and a regular exercise program http://my.webmd.com/encyclopedia/article/2731.1476 |
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| Dosage:- | |||
| The recommended starting dose of Meridia is 10-milligrams administered once daily with or without food. If there is inadequate weight loss, the dose may be titrated after 4 weeks to a total of 15-milligrams taken once daily. The 5-milligram dose should be reserved for those patients that do not tolerate the 10-milligram dose. Blood pressure and heart rate changes should betaken into consideration when making decisions regarding dose titration. Take this medication as prescribed. Do not take it more often or longer than directed. Use in combination with other appetite suppressant medicine is generally not recommended. Take by mouth exactly as directed by your doctor. The full effect on weight may require four to six weeks. Do not increase your dose, take it more frequently or use it for a longer period of time than prescribed because this drug can be habit-forming. Do not suddenly stop using this drug without your doctor's approval. Over time, this drug may not work as well as it did at the beginning. Consult your doctor if weight increases. | |||
| Missed Dosage:- | |||
| If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not "double- up" the dose to catch up. | |||
| Over Dosage:- | |||
| If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose include restlessness, tremor, rapid breathing, nausea, vomiting, diarrhea, and stomach cramps. | |||
| Storage:- | |||
| Store at room temperature between 59 and 86 degrees F (15-30 degrees C) away from light and moisture. Keep this and all medications out of the reach of children. | |||
| Meridia Side Effects:- | |||
Dry mouth, sleeplessness, irritability, back pain, stomach upset or constipation may occur the first few days as you body adjusts to the medication. Stop Meridia if you experience; rash, hives, seizures, worsening of vision, decreased amount of urine or unusual bleeding or bruising. Stop Meridia immediately if you experience the following side effects or symptoms of toxicity; excitement, restlessness, loss of consciousness, confusion, agitation, weakness, shivering, clumsiness or unsteadiness, fast heartbeat, large-unchanging pupils, vomiting, trouble breathing, shortness of breath, chest pains, swelling of feet/ankles or legs, fainting, disorientation, depression, high fever, eye pain, tremor or increased sweating. We stress - if you experience any weird symptoms and or side effects on any diet medication you should immediately stop taking the medication and contact your doctor or patient care at the pharmacy your purchased the pill from. |
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| Contra Indications:- | |||
| Meridia is contraindicated in patients with arteriosclerosis, cardiovascular disease, and moderate to severe hypertension. Tell your doctor of all nonprescription and prescription medication you may use, especially other weight reducing agents (e.g., diethylpropion), drugs that can raise blood pressure such as decongestants (e.g., pseudoephedrine, phenylpropanolamine), cough suppressants (e.g., dextromethorphan), antidepressants (e.g., nefazodone, fluoxetine, paroxetine, sertraline, fluvoxamine, venlafaxine), lithium, psychiatric medications (e.g., MAO Inhibitors such as selegiline, moclobemide, furazolidone, phenelzine, tranylcypromine), drugs for migraines (e.g., dihydroergotamine, sumatriptan), tryptophan, certain narcotic pain relievers (e.g., meperidine, pentazocine, fentanyl), ketoconazole, erythromycin, high blood pressure medicine or any drugs which can cause drowsiness, including certain antihistamines (e.g., diphenhydramine), sedatives and anti-seizure drugs. Antihistamines and decongestants may be found in many nonprescription drugs for cough and cold. Consult your pharmacist. MAO Inhibitors (see above) and this drug should not be taken together. If an MAO Inhibitor or this drug is stopped, wait 2 weeks before starting the other drug. Included on your medical history/personal profile questionnaire all the medicines you use, (prescription and nonprescription), especially other weight reducing agents (e.g., diethylpropion), drugs that can raise blood pressure such as decongestants (e.g., pseudoephedrine, phenylpropanolamine), cough suppressants (e.g., dextromethorphan), antidepressants (e.g., nefazodone, fluoxetine, paroxetine, sertraline, fluvoxamine, venlafaxine), lithium, psychiatric medications (e.g., MAO Inhibitors such as selegiline, moclobemide, furazolidone, phenelzine, tranylcypromine), drugs for migraines (e.g., dihydroergotamine, sumatriptan), tryptophan, certain narcotic pain relievers (e.g., meperidine, pentazocine, fentanyl), ketoconazole, erythromycin, high blood pressure medicine or any drugs which can cause drowsiness, including certain antihistamines (e.g., diphenhydramine), sedatives and anti-seizure drugs. Antihistamines and decongestants may be found in many nonprescription drugs for cough and cold. MAO inhibitors and Meridia should not be taken together. |
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| Pregnancy and Children:- | |||
| It is recommended that women of child-bearing age should use effective birth control while taking this medication. This drug is not recommended for use during pregnancy. Consult your doctor before using this drug. It is not known whether this drug is excreted into breast milk. Because of the potential risk to the infant, breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding. This medication is not suitable for children. Keep this medicine out of the reach of children. | |||
| General Meridia Information:- | |||
| Meridia and Xenical are the only weight-loss medications approved for longer-term use in significantly obese people, although the safety and effectiveness have not been established for use beyond 1 year. Meridia is a short-term drug that helps you to start losing weight and then keep on going when you are ready to carry on, on your own. Your body starts to build up a resistance to the effects of Meridia after a few weeks of treatment, which is when you should be well on your way to a new lifestyle and ready to stop Meridia. Appetite suppressants are not a substitute for proper diet. For maximum effects, this must be used in conjunction with a diet and exercise program. DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS MEDICINE out of the reach of children. Web MD - Meridia / Rreductil (Sibutramine) National Library of Medicine - Meridia / Sibutramine |
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| Other Brand Names:- | |||
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| Miscellaneous:- | |||
| Meridia is pronounced: MER-id-dee-uh Common misspellings or incorrect names of this product include:- Miridia, Meridium, Meridya, Maridia, Miridia, Merida, Meridea, Miridiam and Mererdia. In the UK and Europe Meridia is sold under the brand name Reductil. |
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| Package Insert:- | |||
| The info on Meridia provided on this page is a general guide and is by no means comprehensive. Please read the package insert that comes with your medication. It contains more information about this product. Ensure you follow the instructions provided with your medication and do not exceed the recommended dosages. Should you experience any discomfort, dizziness, shortness of breath or any other side effects contact your physician or the dispensing pharmacy immediately.
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