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| Presentation:- |
Tenuate is a tablet that is used in the short-term management of obesity. It comes in 25-milligram tablet form that is embossed with "Tenuate 25" or "MERRELL 697". Tenuate Dospan is a controlled release 75-milligram tablet that is embossed with the names "Tenuate 75" or "MERRELL 698". |
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| Properties:- |
| Diethylpropion is a sympathomimetic amine, which is similar to an amphetamine. It is also known as an "anorectic" or an "anorexigenic" drug. Diethylpropion stimulates the central nervous system (nerves and brain), which increases your heart rate and blood pressure and decreases your appetite
Tenuate is available for oral administration in immediate-release tablets containing 25 mg diethylpropion hydrochloride and in controlled-release tablets containing 75 mg diethylpropion hydrochloride.
The inactive ingredients in each immediate-release tablet are: corn starch, lactose, magnesium stearate, pregelatinized corn starch, talc, and tartaric acid.
The inactive ingredients in each controlled-release tablet are: carbomer 934P, mannitol, povidone, tartaric acid, zinc stearate.
Diethylpropion hydrochloride is a sympathomimetic agent. The chemical name for diethylpropion hydrochloride is 1-phenyl-2-diethyl-amino-1-propanone hydrochloride.
In Tenuate Dospan tablets, diethylpropion hydrochloride is dispersed in a hydrophilic matrix. On exposure to water, the diethylpropion hydrochloride is released at a relatively uniform rate as a result of slow hydration of the matrix. The result is controlled release of the anorectic agent. |
| Why It Is Used:- |
| Drugs of this class are thought to suppress appetite via a central mechanism (appetite centers in the brain) although this has mechanism has not been clearly proven.
Tenuate is effective therapy for the obese patient who needs to loose weight to decease diseases associated with obesity. The magnitude of the weight loss will depend on the degree of concomitant caloric restriction and the use of a graded exercise program. This medicine is an appetite suppressant used along with diet, exercise, and behavior therapy for the short-term management of obesity. |
| Dosage:- |
| Tenuate Dospan is best taken once a day in the mid morning. This sustained-release or long acting product must be swallowed whole. Crushing or chewing them will destroy the long action and may cause increased side effects. Tenuate (25-milligrams) is best taken on an empty stomach; one hour before breakfast each morning. It may be taken again in mid evening if needed to suppress night hunger. Take this medication as prescribed. Do not take it more often or longer than directed. Use in combination with other appetite suppressant medicine is generally not recommended. Follow the directions for using this medicine provided by your doctor. Take this medicine about 30 minutes to 1 hour before meals. Take your last dose of the day at least 4 to 6 hours before bedtime.
Do not exceed the recommended dose or take this medicine for longer than prescribed without checking with your doctor. Exceeding the recommended dose or taking this medicine for longer than prescribed may cause serious side effects. |
| Missed Dosage:- |
| If you miss a dose of this medicine, take it as soon as possible. If it is after 4 pm, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once. |
| Over Dosage:- |
| If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose include restlessness, tremor, rapid breathing, nausea, vomiting, diarrhea, and stomach cramps. |
| Storage:- |
| Store this medicine at room temperature in a tightly-closed container, away from heat and light. |
| Side Effects:- |
MILD:
Blurred vision, dry mouth, sleeplessness, irritability, stomach upset or constipation may occur the first few days as your body adjusts to the medication. Other adverse events include central nervous system effects, gastrointestinal disturbances, and changes in libido. If these effects persist or become bothersome, you may have to discontinue use. Exercise caution when prescribing anti-obesity drugs for patients with hypertension. If this medication makes you dizzy or lightheaded, avoid driving or engaging in activities requiring alertness. Alcohol can increase unwanted side effects of dizziness. Limit its use.
MODERATE:
Chest pain, pounding heart, difficulty urinating, breathing difficulties or swelling while taking this medication.
SEVERE:
Primary pulmonary hypertension (PPH) and cardiac valvular disease have been reported in patients receiving a combination of phentermine and fenfluramine (phen-fen) or dexfenfluramine. The possibility of an association between PPH and the use of Tenuate alone cannot be ruled out.
Side effects, that may go away during treatment, include restlessness, nervousness, difficulty sleeping, or dry mouth. If they continue or are bothersome, check with your doctor. If you notice other effects not listed above, contact your doctor, nurse, or pharmacist.
We stress - if you experience any weird symptoms and or side effects on any diet medication you should immediately stop taking the medication and contact your doctor or patient care at the pharmacy your purchased the pill from.
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| Contra Indications:- |
| Tenuate is contraindicated in patients with arteriosclerosis, cardiovascular disease, and moderate to severe hypertension.Inform your doctor about all the medicines you use, (prescription and nonprescription) especially if you take high blood pressure medicine or MAO inhibitors (e.g., furazolidone, phenelzine, selegiline, tranylcypromine) or any other weight loss medicine. Decongestants are commonly found in over-the-counter cough and cold medicine. |
| Pregnancy and Children:- |
| This medicine is excreted in breast milk. If you are or will be breast-feeding while you are using this medicine, check with your doctor or pharmacist to discuss the risks to your baby. This medicine is not suitable for children. Keep this medicine out of the reach of children. |
| General Tenuate Information:- |
Tenuate is an appetite suppressant. Xenical inhibits fat absorption into the body. So both may be used in conjunction with each other for those who are seriously obese.
DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS MEDICINE out of the reach of children.
Additional information about phentermine can be found at these links:-
National Library of Medicine - Tenuate Dospan Diethylpropion Inchem.org -Tenuate
Web MD - Tenuate, Tenuate Dospan, diethylpropion
Mediresource - Tenuate
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| Other Brand Names:- |
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| Miscellaneous:- |
Tenuate is pronounced: TEN-you-ate
Common misspellings or incorrect names of this product include:-
Tennuate, Tenuaite, Tenuatte, Tenueight, Tanuate, Tenu8, Tenu - 8, Tenu 8, Tenuat, Tenuait and Tenuyt.
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| Package Insert:- |
The information provided on this page is a general guide and is by no means comprehensive. Please read the package insert that comes with your medication. It contains more information about Tenuate.
Ensure you follow the instructions provided with your medication and do not exceed the recommended dosages.
Should you experience any discomfort, dizziness, shortness of breath or any other side effects contact your physician or the dispensing pharmacy immediately.
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